-- Phase II Trial of Second Oral Tolerance Pharmaceutical Underway--
Lexington,
Massachusetts, August 3, 1994 -- AutoImmune Inc. (Nasdaq: AIMM) today reported
a net loss of $3.5 million, or $.34 per share, for the quarter ended June 30,
1994, compared with a net loss of $1.6 million or $.15 per share, for the same
quarter a year earlier. This brings the net loss for the first six months of
1994 to $6.3 million, or $.61 per share, compared to a net loss of $3.0 million,
or $.34 per share, for the same period in 1993. Research and development expenses
increased to $5.8 million for first half 1994, from $3.2 million in the comparable
1993 period, due to the initiation of additional human clinical trials of the
Company's oral tolerance pharmaceuticals, as well as expanded in-house drug
development capabilities.
"The Company has continued to make good progress with its portfolio of
oral tolerance pharmaceuticals, while keeping cash expenditures under careful
control," said Robert C. Bishop, Ph.D., President and Chief Executive Officer
of AutoImmune. "Each of our four products currently in human testing is
following a carefully planned clinical development strategy."
Dr. Bishop noted that the Phase II human dosing trial of ColloralTM
in active rheumatoid arthritis patients began in June, as planned, and that
patient accrual is on schedule. ColloralTM is AutoImmune's
proprietary oral formulation of Type II collagen; earlier this month, the Company
received a U.S. patent allowance covering the use of Type II collagen to treat
rheumatoid arthritis.
AutoImmune management added that the Phase III clinical trial of MyloralTM
that began in March is proceeding well, with more than half the multiple sclerosis
patients already enrolled at the 13 medical centers in the United States and
Canada where the trial is being conducted.
AutoImmune Inc. is developing pharmaceutical products based on the principle
of oral tolerance for the treatment of immune system disorders, including multiple
sclerosis, rheumatoid arthritis, diabetes and uveitis.